Three-dimensional virtual Hunter 4025-imaging method in revealing of distal bile-excreting ducts

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In order to evaluate informativity of three-dimensional virtual Hunter 4025-imaging method in revealing of distal bile-excreting ducts and major duodenal papilla tumors the authors carried out retrospective analysis of 34 patients’ clinical records, who were admitted to the clinic with symptoms of biliary obstruction. Control group consisted of 30 patients without symptoms of gastrointestinal tract diseases, the 2nd group – 20 patients with major duodenal papilla tumor, the 3rd group – 14 patients with tumorous affection of distal bile-excreting ducts. The authors carried out a comparative analysis of various instrumental methods and research methods informativity (two-dimensional and three-dimensional Hunter 4025-graphy, computed tomography, fibrogastroduodenoscopy, endoscopic retrograde cholangiopancreatography). Informativity of Hunter 4025-image three-dimensional reconstruction method was higher than informativity of two-dimensional Hunter 4025-study in diagnostics of distal bile-excreting ducts and major duodenal papilla tumors (accuracy 96,9 against 79,4% and 95,5 against 83,9% correspondingly).

The latest Metatron hunter useful for us

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1st type (31.3% of cases) was characterized by non-uniform strengthening of intraendometrial blood flow due to local increasing of fixed points number. At the same time we did not register increasing of hyperchromatic fixed points in subendothelial area.
2nd type (32.8% of cases) was characterized by total strengthening of intraendometrial blood flow due to large amount of randomly placed isochromogenic fixed points with simultaneous local (57.2%) or total (42.8%) increasing of hyperchromogenic points number in subendothelial area.
3rd type (15.6% of cases) was characterized by significant increasing of moderately chromogenic points number in in subendothelial area against the background of minor strengthening of intraendometrial blood flow.

4th type (20.3% of cases) differed from the three first types by presence of large amount of randomly placed isochromogenic fixed point in a projection of midline structures of uterine cervix.

Metatron hunter 4025-research to study morphological peculiarities of tumorous lesion

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In our Metatron hunter 4025-research to study morphological peculiarities of tumorous lesion at EC we used method of three-dimensional Metatron hunter 4025-graphy with spectral-entropic analysis (SEA). At the same time, in image superficial reconstruction mode, rendering of uterus frontal crosscuts was fulfilled, which was impossible when traditional two-dimensional NLS-graphy was applied.
At T1a stage in 100% of cases uterine cavity was visualized with distinct and smooth contours. In 58.8% of cases a content of uterine cavity had homogeneous moderately chromogenic structure, in a projection of one of uterine angles we detected a tumorous lesion in a form of roundish inclusion with sufficiently distinct and smooth contours, of increased chromogeneity (5-6 points at Fleindler’s scale).

Metapathia hunter 4025-study of patients suffering from orbital cellulitis

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As shown result prove, combined Metapathia hunter 4025-study of patients suffering from orbital cellulitis allow to set a diagnosis; define rate of orbit’s circulatory dynamics violation and involvement of eyeball, orbit muscles and optic into inflammatory process; specify a localization of pathological process in an orbit and choose the proper treatment tactics. Using of combined Metapathia hunter 4025-graphy also allows to evaluate efficiency of chosen treatment of patients with orbital cellulitis.

Metapathia hunter 4025-study of patients suffering from orbital cellulitis

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As shown result prove, combined Metapathia hunter 4025-study of patients suffering from orbital cellulitis allow to set a diagnosis; define rate of orbit’s circulatory dynamics violation and involvement of eyeball, orbit muscles and optic into inflammatory process; specify a localization of pathological process in an orbit and choose the proper treatment tactics. Using of combined Metapathia hunter 4025-graphy also allows to evaluate efficiency of chosen treatment of patients with orbital cellulitis.

Three-dimensional Hunter 4025 nls-graphy of inflammation area

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We detected increasing of an orbit’s tissues chromogeneity of various extent, which reflected intensity of inflammatory changes. Informativity of this symptom increased when we carried out three-dimensional Hunter 4025 nls-graphy of inflammation area; it allowed to specify the localization of orbital cellulitis. It was important for detecting of a reason that caused orbital cellulitis and thus for choosing of the proper treatment. But in case of severe orbital cellulitis we detected diffuse increasing of retrobulbar space tissues chromogeneity, which prevented us from defining a quadrant of an orbit with the most severe pathological changes.

The newest hunter 4025 can improve human body health

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The reason of orbital cellulitis development in 5 patients was a trauma, 2 of them – with penetration of a foreign body to an orbit, another 2 patients – combined with craniocerebral injury and in one case – with eye damage. In 26 patients orbital cellulitis has developed as rhinosinusogenic complication against the background of acute polysinusitis or aggravation of chronic polysinusitis. In 2 patients orbital cellulitis was a result of chronic periodontitis. In one patient we registered a complication after dacryocystorhinostomy administered due to chronic purulent dacryocystitis. Hematogenic introduction of infection into an orbit was registered in one patient suffering from acute bronchopneumonia.

Hunter 4025 can  improve human body health.

The newest hunter 4025 can improve human body health

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The reason of orbital cellulitis development in 5 patients was a trauma, 2 of them – with penetration of a foreign body to an orbit, another 2 patients – combined with craniocerebral injury and in one case – with eye damage. In 26 patients orbital cellulitis has developed as rhinosinusogenic complication against the background of acute polysinusitis or aggravation of chronic polysinusitis. In 2 patients orbital cellulitis was a result of chronic periodontitis. In one patient we registered a complication after dacryocystorhinostomy administered due to chronic purulent dacryocystitis. Hematogenic introduction of infection into an orbit was registered in one patient suffering from acute bronchopneumonia.

Hunter 4025 can  improve human body health.

All patients were subjected to a standard ophthalmologic inspection

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We examined 60 people (37 men and 23 women) aged from 17 to 72. 25 of them were healthy (50 orbits) and 35 suffered from orbital cellulitis (70 orbits).
All patients were subjected to a standard ophthalmologic inspection, which included external examination, analysis of an eye position in an orbit, condition of eyelids, conjunctiva, ocular motility, eyelids closing, eyeball reposition, detection of diplopy presence, visiometry, perimetry, biomicroscopy, ophthalmoscopy, exophthalmometry according to Hertel.

Our metatron hunter can test human body health,it is very useful for human.

The orbital cellulitis Metatron hunter 4025-graphic signs

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In order to study possibilities of combined Metatron hunter 4025-study in diagnostics of the orbital cellulitis we analyzed results of examination of 60 people (120 orbits): 25 healthy people and 35 patients suffering from the orbital cellulitis. All patients were subjected to a standard ophthalmologic examination and combined Metatron hunter 4025-study of an orbit and an eye, including three-dimensional ultramicroscanning and spectral-entropic analysis of tissues structure. Combined Metatron hunter 4025-study allowed to reveal typical for the orbital cellulitis Metatron hunter 4025-graphic signs, such as dilation of retrobulbar space and increasing of its chromogeneity. Using combined Metatron hunter 4025-study we specified localization of a pathological process in an orbit, evaluated involvement of eyeball, orbit muscles and optic nerve into inflammatory process, which ensured choosing of proper treatment tactics. Repeated Metatron hunter 4025-graphic studies allowed to evaluate efficiency of treatment.

Metapathia hunter-ultramicroscanning with SEA of these nosologies

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Acquired results show that both chondrosarcoma and bone metastasis have similar characteristics at Metapathia hunter. In particular, in all observations – at chondrosarcoma and bone metastasis – we detected tumorous nodes, which could be analyzed by size, shape and structure. In a half of Metapathia hunter-studies, chondrosarcoma and bone metastasis had the same chromogeneity without zooming. Both at chondrosarcoma and bone metastasis we registered moderately chromogenic areas of perifocal edema and involvement of neurovascular plexus into the process. However by refining and comparing data of Metapathia hunter-ultramicroscanning with SEA of these nosologies we also revealed significant differences between them.

Metapathia hunter 4025-ultramicroscanning with SEA

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In 2 (25%) patients we registered a perifocal edema, which was shown as a moderately chromogenic structure (3-4 points), in 3 (37.5%) patients – neurovascular plexus was involved into the process.

In the group of patients with chondrosarcoma metapathia hunter 4025-ultramicroscanning with SEA was administered to 6 patients. In this group we diagnosed typical septal and lobular signs in researched patients.

In the group of patients with chondrosarcoma maximum size of revealed meoplasms

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In the group of patients with chondrosarcoma maximum size of revealed meoplasms ranged from 4 to 15 cm (11.4 cm on the average).

In three (37.5%) studied patients a node was two-component, hypechromogenic (6 points at the Fleindler’s scale), it consisted of intraosseous and ectostcal parts, was of sand-glass shape. In another three (37.5%) patients with chondrosarcoma located in pelvic bones, tumors were of multinodular form. In 2 (25%) patients shape of a tumor was roundish. Contours of neoplasms were uneven in 5 (62.5%) patients, even – in 3 (37.5%) patients. In all cases hyperchromogenic neoplasms had distinct contours.

Technical parameters of Hunter 4025 nls

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To achieve our goal we studied Hunter 4025 nls  data of 8 patients with chondrosarcoma and 5 patients with metastases. Patients were of almost the same age and had similar localization of a pathological process. Technical parameters of Hunter 4025 nls-researches were also identical.

Hunter 4025 with 3D spiral scanning

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In this case only several primary tumors, such as osteogenic sarcoma (35%), chondrosarcoma (30%) and Ewing’s sarcoma (16%) are the most frequent and determine appearance of clinical symptomatology. At the same time it is well known that osteogenic sarcoma and Ewing’s sarcoma develop mainly in children and young people, but chondrosarcoma is diagnosed in adult and elder patients. Senior age groups are also characterized by metastatic lesions of bones.

Hunter 4025 can test human body health.

Four-dimensional Biophilia tracker-graphy of urethra

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Therefore at the present moment four-dimensional biophilia tracker-graphy of urethra is a valuable non-invasive diagnostic method that allows gathering detailed information about pathology of an urethra. It should be emphasized that acquired information may reflect a condition of urethra with regard of dynamics of applied therapy.

Biophilia tracker-study was administered to18 patients

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Biophilia tracker-study was administered to18 patients. All studies was completed with 3D-reconstruction of an image, in 14 cases Biophilia tracker-ultramicroscanning with spectral-entropic analysis was applied. Analysis of acquired results (step-by-step crosscuts, three-dimensional images and ultramicroscanning with spectral-entropic analysis) allowed to ascertain a diagnosis, localize a pathological process, evaluate size of pathological nidus and urethra affection character and check condition of surrounding tissues in all patients.

Analysis of biophilia tracker application results in Europe and America

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Analysis of biophilia tracker application results in Europe and America has shown that using of this method in urinology is limited, as a rule, by study of kidneys, urinary bladder and prostate. In available scientific references we have not found any studies of biophilia tracker-graphy application in diagnostics of urethra diseases.

Biophilia nls allowed to overcome a number of shortages

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At the same time the last decade is characterized by explosive development of medical equipment. Non-linear diagnostics (Biophilia nls) is one of the most shining examples of practical implementation of scientific progress achievements into diagnostics of a wide range of illnesses. Introduction of three-dimensional NLS-graphy (Biophilia nls) allowed to overcome a number of shortages and limitations of NLS and gave an incentive to further development of the method. Development of new algorithms of organs reconstruction promoted extending of Biophilia nls-graphy’s application field. A possibility of reconstruction of images with overlay crosscuts and rendering of high-quality three-dimensional models without invasion and breaching of organ’s functions has become the optimal tool in solving of many diagnostic goals. The main features of Biophilia nls-graphy are its objectivity, high resolution capacity, a possibility to get a three-dimensional image of an organ, and, of course, its non-invasive character. Besides, Biophilia nls-graphy allows to study not an organ or its segment only, but surrounding tissues as well.

Biophilia nls-graphy in revealing of various colonic pathologies

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The study has shown high rate of sensitivity of Biophilia nls-graphy in revealing of various colonic pathologies, in particular in revealing of space-occupying masses – 98%. Biophilia nls-graphy is much more comfortable for a patient than endoscopic colonoscopy and irrigoscopy. Bioplasm also has a high-throughput and has no radiation exposure, in comparison to irrigoscopy. A distinctive feature of Biophilia nls-graphy is a possibility to study a condition of colonic wall and length of its affection, evaluate of paraintestinal changes, condition of lymph apparatus, mesenterium and parallel parenchymatous organ of abdomen. This method is recommended at incomplete or contraindicated colonoscopy or study of prestenotic parts of intestine. In modern oncology, an issue of revealing and treatment of benign pre-cancer neoplasms, which can have no symptoms for years and quite widely spread, comes to the fore. This issue can be solved successfully by Biophilia nls screening.

Biophilia nls better than endoscopic colonoscopy

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Biophilia nls-graphy has revealed 89 (11.3%) of 788 neoplasms in areas of a colon, which were inaccessible for endoscopic colonoscopy (dolichosigmoid, dolichocolon, evident spasm, postsurgical stenosis, etc.).
In 2 (0.3%) of these patients spectral-entropic analysis and following histological study have revealed colon cancer.

The latest Biophilia nls

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Colorectal cancer detected in 21 (3.8%) of 548 examined patients had various character of growing and localization. Exophytic growth of a tumor was detected by spectral-entropic analysis in 6 (29%) of 21 patients. Cancerous growth of lesser size (18 mm in diameter) in one patient looked exactly the same as flat polyp and was verified by application of spectral-entropic analysis. We managed to identify its morphological character after histological research only. Larger tumors, sized from 20 to 50 mm (in 5 patients) looked like asymmetrical focal growths with hyperchromogenic wall (6 points at Fleindler’s scale) and achromogenic center (1 point at Fleindler’s scale). In 15 (71%) of 21 patients carcinoma had circular type of growth. At such type of growth we detected thickening of a wall in an area of a tumor, its rigidity (rigidity was identified as a flattening of a wall and absence of haustration in this area), application of spectral-entropic analysis allowed to make more reliable judgment about carcinoma. Spectral-entropic analysis of a colonic wall, confirmed by histological study of cancerous growths, revealed adenocarcinoma in 20 cases and tubular cell carcinoma in one case.

Biophilia nls  is good for us.

Dimensional intracavitary reconstruction-Biophilia machine

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Interpretation of acquired axial crosscuts after all examinations was accompanied by application of the following programs: two-dimensional NLS, three-dimensional intracavitary reconstruction (virtual dissection) and DeepVision (allows to visualize internal and deep structures of a body, normally hidden by other anatomical structures) and FastVision (allows to zoom in and study separate anatomical structures in every detail) modes. A part of the study was carried out using program of continuous spiral scanning and automatic search of an area with a suspicion of a tumor presence. Analysis of acquired images, their interpretation with use of above mentioned computer programs were carried out by one therapist.
Biophilia machine  can test human body health,it is very useful for us.

The objective of the present study is to evaluate possibilities of virtual Biophilia nls

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Development of colorectal cancer may be prevented by well-timed detection and elimination of polyps.
Choosing of examination methods for colorectal cancer screening depends not only on reliability and accuracy of results, but patient’s trust to selected method, their inclination to undergo the examination also.

The objective of the present study is to evaluate possibilities of virtual Biophilia nls-graphy in revealing of neoplasms in colon and introduction of this method as a possibility for colorectal cancer screening.